Units

Transfusion Medicine

    Dr Shirley Phyllis Owusu- Ofori

                       Head of Unit

The Transfusion Medicine Unit (TMU) provides blood transfusion support in terms of blood and blood components for clinical use in Komfo Anokye Teaching Hospital and other health care facilities in the Ashanti Region and beyond. The Unit seeks to provide a steady regular supply of safe blood to patients requiring blood as a therapeutic intervention. Established in 2002, the Unit operates under the Medical Director’s ambit.

The TMUis headed by Dr Shirley Phyllis Owusu- Ofori (nee Opoku), a Transfusion Medicine Consultant.

 

Other management team members are:

 

Technical Head – Labs Section               Dr. Francis Sarkodie

Head – Donor Care Section                    Ms. Stella Manu

Head – Donor Organisation Section       Mr. Kwame Asenso Mensah

Administrative Manager                          Ms. Alice Antwi

 

Currently, 80% of total blood collections in KATH, emanates from voluntary non-remunerated blood donors with a repeat voluntary donor population of 30%.

The unit continually strives to increase voluntary blood donations and has initiated a drive to convert family replacement donors into altruistic voluntary donors.

 

SERVICES:

a. Donor Organization

 

The TMU offers services including Donor Organization which involves the planning of mobile blood collecting sessions, recruiting and retaining voluntary blood – donors, attracting new areas i.e. work areas, groups etc for blood collection.

 

b. Laboratory Services

Transfusion–Transmissible Infection screening assays namely anti-HIV, HBsAg, anti-HCV and Syphilis antibody tests are carried out under quality-assured means on all blood units for patient care.

Immuno-haematology services include Blood grouping serology for both patients and donors, Compatibility testing of blood units for patients, Antibody investigations and Investigations for adverse transfusion reactions.

Blood and Blood components provided by the unit are Concentrated Red cells, Whole Blood, Fresh Frozen Plasma, Cryoprecipitate and Platelet concentrates.

 

 

 

c. Donor Clinic

 

The Donor Clinic offers Pre and Post Donation Counseling to prospective and deferred blood donors respectively. Therapeutic Venesections are carried out for referred patients. Pre-Operative Autologous Blood Donation services are available for well-informed elective patients from either of the surgical disciplines. It is very much encouraged that this service will be patronized tremendously to reduce over-reliance on allogeneic blood.

       

CLINICAL SUPPORT:

The TMU assists clinical care with appropriate use of blood guidance on a daily walk-in basis. Consults are available also for Transfusion related clinical issues and the management of special transfusion related cases. A Haemovigilance program has been initiated with the support of Terumo BCT and JICA in three departments; Oncology, Paediatrics and Obstetrics and Gynaecology. The ultimate goal is to roll it out successfully across all the Clinical Departments in KATH.

 

TRAINING:

The Transfusion Medicine Unit continues to play a vital role in the In-service training of most categories of health workers on Blood related issues such as Procedures for Requesting Blood, Collection and Storage of Blood, Administration etc. The unit has trained several batches of Phlebotomists who render quality services across the hospital to relieve clinical areas and laboratories of the pressure of long waiting times for clients and donors.

 

The unit also plays a vital role in the induction training of Intern doctors and pharmacists by introducing them to the basic rudiments of a safe transfusion practice. Practical support is offered to students training and preparing towards their Bachelor of Science degree in Medical Laboratory Technology. Part-time teaching of Clinical Medical students in Transfusion Medicine is also offered by the unit.

 

 

HUMAN RESOURCE CAPACITY:

Our current crop of staff are as follows:

 

Unit Head                                                                   1

Admin. Manager                                                        1

Accountant                                                                1

Medical Lab. Scientists                                             12

Technical Officers                                                     8

Blood Donor Organisers                                          5

Nurses                                                                       7

HCA/Phlebotomists                                                 10

Orderlies                                                                   2

Total                                                                         47

 

RESEARCH ACTIVITIES:

The unit has contributed over the years in building research capacity and providing local blood transfusion evidence in Ghana and Sub-Sahara from several studies carried out. Several international institutions who have forged strong research collaborations with the unit include Division of Transfusion Medicine, Department of Haematology of the University of Cambridge and Liverpool School of Tropical Medicine, Liverpool. Organizations like Sliagen LLC, Austin, Texas and recently Terumo BCT Inc, Europe have had fruitful research engagements with the Transfusion Medicine Unit in carrying out research activities aimed at improving blood safety.  A landmark clinical trial, African Investigation of the Mirasol System (AIMS) was conducted with Terumo BCT and it was demonstrated that the transmission of malaria through blood transfusion could be significantly reduced using the Mirasol technology. As a result of this study the Mirasol Whole Blood (WB) system was CE marked in September 2015. This has culminated in the implementation of the Mirasol Whole Blood Pathogen Reduction Technology in two teaching Hospitals (Korle-Bu and Komfo Anokye) in Ghana.

 

PUBLICATIONS:

1.    Microchimerism in Ghanaian children recipients of whole blood transfusion for severe anaemia

Assennato SM, Owusu-Ofori S, Osei-Akoto A, Lambert NC, Allain JP. Vox Sang. 2019 Feb; 114 (2):162-170. doi: 10.1111/vox.12734. PMID. 30523635

 

2.    Improving the screening of blood donors with syphilis rapid diagnostic test (RDT) and rapid plasma reagin (RPR) in low- and middle-income countries (LMIC).

Sarkodie F, Hassall O, Owusu-Dabo E, Owusu-Ofori S, Bates I, Bygbjerg IC, Owusu-Ofori A, Harritshøj LH, Ullum H. Transfus Med. 2017 Feb; 27(1):52-59. doi: 10.1111/tme.12363

 

3.    Detection of adverse events of transfusion in a teaching hospital in Ghana.

Owusu-Ofori AK, Owusu-Ofori SP, Bates I. Transfus Med. 2017 Jan 31. doi: 10.1111/tme. 12392. PMID: 28139022

 

4.    Characterization of posttransfusion Plasmodium falciparum infection in semi-immune nonparasitemic patients.

Allain JP, Assennato SM, Osei EN, Owusu-Ofori AK, Marschner S, Goodrich RP, Owusu-Ofori S. Transfusion. 2016 Sep; 56(9):2374-83. doi: 10.1111/trf.13706.

 

5.    Effect of Plasmodium inactivation in whole blood on the incidence of blood transfusion-transmitted malaria in endemic regions: the African Investigation of the Mirasol System (AIMS) randomised controlled trial.

Allain JP, Owusu-Ofori AK, Assennato SM, Marschner S, Goodrich RP, Owusu-Ofori S. Lancet. 2016 Apr 23; 387 (10029):1753-61. doi:

6.    A novel strategy for screening blood donors for syphilis at Komfo Anokye Teaching Hospital, Ghana.

Sarkodie F, Ullum H, Owusu-Dabo E, Owusu-Ofori S, Owusu-Ofori A, Hassall O.

Transfus Med. 2016 Feb; 26(1):63-6. doi: 10.1111/tme.12279. PMID: 26834072

 

7.    Fourteen-year experience of a tertiary hospital transfusion committee in West Africa.

Opare-Sem O, Bedu-Addo G, Karikari P, Boateng P, Sarkodie F, Rahman R, Asenso-Mensah K, Awuah B, Osei Akoto A, Munin SA, Mensah-Acheampong F, Allain JP, Owusu-Ofori S. Transfusion. 2014 May 20. doi: 10.1111/trf.12690. PMID: 24845344

 

8.    Appropriateness of blood product transfusion in the Obstetrics and Gynaecology (O&G) department of a tertiary hospital in West Africa.

Osei EN, Odoi AT, Owusu-Ofori S, Allain JP. Transfus Med. 2013 Jun; 23(3):160-6. doi: 10.1111/tme.12028.PMID: 23672710

 

9.    Can family or replacement blood donors become regular volunteer donors?

Asenso-Mensah K, Achina G, Appiah R, Owusu-Ofori S, Allain JP. Transfusion. 2014 Mar; 54(3 Pt 2):797-804. doi: 10.1111/trf.12216.PMID: 23614450

10. Investigating the prevalence of transfusion transmission of Plasmodium within a hyperendemic blood donation system.

Freimanis G, Sedegah M, Owusu-Ofori S, Kumar S, Allain JP. Transfusion. 2013 Jul; 53(7):1429-41. doi: 10.1111/j.1537-2995.2012.03943.x..PMID: 23113534

Email: transfusion@kathhsp.org 

               : sowusu-ofori@kathhsp.org 

Contact Numbers:

Direct line                                   00233 3220 23003

Reception                                   00233 3220 22301-3 ext 2067

Head of Unit:                              00233 3220 22301-3 ext 2010

Immunoheamatology lab              00233 3220 22301-3 ext 2070

Donor Clinic                               00233 3220 22031-3 ext 1265

Donor Organiser’s Office              00233 3220 22031-3 ext 1224

Admin. Manager’s Office              00233 3220 22031-3 ext 1276

Emergency Lines: Lab                 00233 508874341

                  Donor Care                00233 508874351

                  Donor Services           00233 502735096

 

 

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SUPPORT KATH ENDOWMENT FUND

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Bank Account Number 

Fidelity Bank : 1300031981548

Ecobank : 0219104402432601

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